What is the nature of work conducted by the various individual stakeholders within the grants-supported research enterprise and what are the most effective ways to model and analyze these work processes?

How does this work change when conducted in an interorganizational arena?

How can modeling tools capture sophisticated interorganizational group processes?

Can complex organizational and interorganizational policies be adequately described and used effectively within workflow systems?

How can workflow technologies support dynamic workflow changes?

What technical architectures support collaboration and what applications are needed to integrate workflow across interacting, but separate, organizations?